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No Simethicone

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POEM (Parent Oriented Evicence Medicine)

One common medications that mothers use of their colicky baby is Simethicone. It comes in many brand names of gas. I do not recommend it because there is a controlled randomized trial that shows placebo is as effective as Simethicone. Here is the abstract proving that:


Pediatrics. 1994 Jul;94(1):29-34.


      
Simethicone in the treatment of infant colic: a randomized, placebo-controlled, multicenter trial.

Metcalf TJ, Irons TG, Sher LD, Young PC.

Willow Creek Pediatrics, Salt Lake City, UT.

OBJECTIVE. To  determine the efficacy of simethicone in the treatment of infant colic. DESIGN.  Randomized, double blind, placebo-controlled. SETTING. Three general pediatric  practices in distinct geographic regions. PATIENTS. Eighty-three infants between  2 and 8 weeks of age with infant colic. INTERVENTIONS. Treatment with  simethicone and placebo in double blind crossover fashion. RESULTS. A total of 166 treatment periods, ranging from 3 to 10 days, were evaluated in the 83  infants. Compared to baseline, improvement in symptoms was reported for 54% of  the treatment periods, worsening was reported for 22%, and, for 24%, there was  no change. The likelihood of the treatment period being rated as showing  improvement, worsening, or no change was the same whether the infant was receiving placebo or simethicone. Twenty-eight percent of he infants responded  only to simethicone, 37% only to placebo, and 20% responded to both. No statistically significant differences were noted among these three groups of responders. No difference could be shown even when infants with "gas-related  symptoms" (by parental report) were separated out as a group. CONCLUSION. Although both produced perceived improvements in symptoms, simethicone is no  more effective than placebo in the treatment of infantile colic.

Publication Types:

  • Clinical Trial
  • Randomized Controlled Trial


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