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Causes of Feeding Disorders Leo Leonidas MD, FAAP
Why Have a List of Differential Diagnosis?
It is important for clinicians to frequently refer
to a list of differential diagnosis so they could
ask good questions from the patient or parent. A
good clinical history depends on a complete list of
differential diagnosis of the chief complaint or
main problem.
DISORDERS THAT AFFECT APPETITE, FOOD-SEEKING BEHAVIOR, AND INGESTION
Depression Deprivation CNS disease (diencephalic syndrome) Poverty (inadequate food available)
METABOLIC DISEASES
Hereditary Fructose Intolerance Urea Cycle Disorders Organic Acidemias
SENSORY DEFECTS
Anosmia Blindness Neuromuscular Disease Oral hypersensitivity or aversion resulting from a lack of feeding experience during crucial sensitive periods (long-term parenteral or enteral tube feeding)
CONDISIONED DYSPHAGIA
Aspiration Oral Inflammation Gastroesophageal Reflux Dumping syndrome or gastric bloating after gastric surgery Fatigue (heart disease, lung disease)
ANATOMIC ABNORMALITIES OF THE OROPHARYX
Clip lip and/or palate Macroglossia Ankyloglossia Pierre Robin Syndrome Retropharyngeal mass or abscess Velophryngeal insufficiency Tonsillar Hypertrophy Dental Caries
ANATOMIC/CONGENITAL ABNORMALITIES OF THE LARYNX & TRACHEA
Laryngeal cleft Laryngomalacia Laryngeal cyst Subglotic stenosis Tracheomalacia Tracheoesophageal compression from vascular ring/sling
ANATOMIC ABNORMALITIES OF THE ESOPHAGUS
Traheoesophageal fistula Congenital esophageal atresia Congenital esophageal stenosis because of traheobronchial remnnats Esophageal stricture, web, or ring Esophageal mass or tumor Foreign body Vascular rings and dysphagia lusorum
DISORDERS AFFECTING SUCK-SWALLOW-BREATHING COORDINATION
Choanal atresia Bronchopulmonary dysplasia Cardiac Disease Tachypnea (respiratory rate > 60 breaths/min)
DISORDERS AFFECTING NEUROMUSCULR COORDINATION OF SWALLOWING
Cerebral Palsy Bulbar atresia or palsy Brain stem glioma Arnold-Chiari malformation Myelomeningocele Familial dysautonomia Tardive dyskinesia Nitrazepam-induced dysphagia Postdiphtheretic and polio paralysis Mobius syndrome Myasthenia gravis Infant botulism Congenital myotonic dystrophy Oculopharyngeal dystrophy Muscular dystrophies and myopathies Cricopharyngeal achalasia Poliomyositis/dermatomyositis Rheumatoid arthritis
DISORDERS AFFECTING ESOPHAGEAL PERISTALSIS
Achalasia Chgas disease Diffuse esophageal spasm Pseudo-obstruction Scleroderma Mixed connective tissue disease Systemic lupus erythematosus Polymositis/dermatomyositis Rheumatoid arthritis
MUCOSAL INFECTIONS AND INFLAMMATORY DISORDERS CAUSING DYSPHAGIA
Adenotonsillitis Deep neck space infections Epiglottis Laryngopharyngeal reflux from gastroesophageal reflux Gastroesophageal reflux Caustic ingestion Candida pharyngitis or esophagitis Herpes simples esophagitis HIV Cytomegalovirus esophagitis Chrohn's disease Bechet disease Chronic graft-versus-host disease
OTHER MISCELLANEOUS DISORDERS ASSOCIATED WITH FEEDING AND SWALLOWING DIFFICULTIES
Xerostomia Hypothyroidism Neonatal hyperparathyroidism Idiopathic neonatal hypercalcemia Trisomy 18 and 21 Velocardiofacial syndrome Rett syndrome Prader-Willi syndrome Allergies Lipid and lipoprotein metabolism disorders Neurofibromatosis Williams syndrome Coffin-Siris syndrome Optiz-G syndrome Cornelia de Lange syndrome Interstitial deletion (q21.3q31) Globus sensation Epidermolysis bullosa dystrophica
Reference: PEDIATRIC CLINICS OF NORTH AMERICA, Feb. 2002, page 98
Belly Pain Air Leaks From Lungs Acute Crying Back Pain Bed Wetting Big Lymph Node Big Spleen Blood in Urine Chronic Diarrhea Chest Pain Cough Coughing Up Blood Constipation Droopy Eye Enlarged Glands Eye Swelling Excessive Thrist Facial Paralysis Fainting Spell Feeding Problem GI Bleeding Headache Head Tilt Hives High ESR Hoarseness Joint Pain Limp Leg Pain Muscle Weakness Noisy Breathing Nose Bleeding Nose Obstruction Pyuria Recurrent Infection Red Green Urine Ringing in the Ears Scrotal Swelling Seizures Stiff Neck Swelling of the Parotic Gland Toe Walking Toeing In Toeing Out Unequal Pupils Vomiting Wheezing
Leo Leonidas, MD, FAAP Assistant Clinical Professor in Pediatrics Tufts University School of Medicine, Boston
Attending Pediatrician Eastern Maine Medical Center, Bangor
Bangor, ME: First City with EBPP (Evidence Based Pediatrics for Parents) Website
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