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Feeding Problems

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Causes of Feeding Disorders
Leo Leonidas MD, FAAP

Why Have a List of Differential Diagnosis?

It is important for clinicians to frequently refer to a list of differential diagnosis so they could ask good questions from the patient or parent. A good clinical history depends on a complete list of differential diagnosis of the chief complaint or main problem.

DISORDERS THAT AFFECT APPETITE, FOOD-SEEKING BEHAVIOR, AND INGESTION

Depression
Deprivation
CNS disease (diencephalic syndrome)
Poverty (inadequate food available)

METABOLIC DISEASES

Hereditary Fructose Intolerance
Urea Cycle Disorders
Organic Acidemias

SENSORY DEFECTS

Anosmia
Blindness
Neuromuscular Disease
Oral hypersensitivity or aversion resulting from a lack of feeding experience during crucial sensitive periods (long-term parenteral or enteral tube feeding)

CONDISIONED DYSPHAGIA

Aspiration
Oral Inflammation
Gastroesophageal Reflux
Dumping syndrome or gastric bloating after gastric surgery
Fatigue (heart disease, lung disease)

ANATOMIC ABNORMALITIES OF THE OROPHARYX

Clip lip and/or palate
Macroglossia
Ankyloglossia
Pierre Robin Syndrome
Retropharyngeal mass or abscess
Velophryngeal insufficiency
Tonsillar Hypertrophy
Dental Caries

ANATOMIC/CONGENITAL ABNORMALITIES OF THE LARYNX & TRACHEA

Laryngeal cleft
Laryngomalacia
Laryngeal cyst
Subglotic stenosis
Tracheomalacia
Tracheoesophageal compression from vascular ring/sling

ANATOMIC ABNORMALITIES OF THE ESOPHAGUS

Traheoesophageal fistula
Congenital esophageal atresia
Congenital esophageal stenosis because of traheobronchial remnnats
Esophageal stricture, web, or ring
Esophageal mass or tumor
Foreign body
Vascular rings and dysphagia lusorum

DISORDERS AFFECTING SUCK-SWALLOW-BREATHING COORDINATION

Choanal atresia
Bronchopulmonary dysplasia
Cardiac Disease
Tachypnea (respiratory rate > 60 breaths/min)

DISORDERS AFFECTING NEUROMUSCULR COORDINATION OF SWALLOWING

Cerebral Palsy
Bulbar atresia or palsy
Brain stem glioma
Arnold-Chiari malformation
Myelomeningocele
Familial dysautonomia
Tardive dyskinesia
Nitrazepam-induced dysphagia
Postdiphtheretic and polio paralysis
Mobius syndrome
Myasthenia gravis
Infant botulism
Congenital myotonic dystrophy
Oculopharyngeal dystrophy
Muscular dystrophies and myopathies
Cricopharyngeal achalasia
Poliomyositis/dermatomyositis
Rheumatoid arthritis

DISORDERS AFFECTING ESOPHAGEAL PERISTALSIS

Achalasia
Chgas disease
Diffuse esophageal spasm
Pseudo-obstruction
Scleroderma
Mixed connective tissue disease
Systemic lupus erythematosus
Polymositis/dermatomyositis
Rheumatoid arthritis

MUCOSAL INFECTIONS AND INFLAMMATORY DISORDERS CAUSING DYSPHAGIA

Adenotonsillitis
Deep neck space infections
Epiglottis
Laryngopharyngeal reflux from gastroesophageal reflux
Gastroesophageal reflux
Caustic ingestion
Candida pharyngitis or esophagitis
Herpes simples esophagitis
HIV
Cytomegalovirus esophagitis
Chrohn's disease
Bechet disease
Chronic graft-versus-host disease

OTHER MISCELLANEOUS DISORDERS ASSOCIATED WITH FEEDING AND SWALLOWING DIFFICULTIES

Xerostomia
Hypothyroidism
Neonatal hyperparathyroidism
Idiopathic neonatal hypercalcemia
Trisomy 18 and 21
Velocardiofacial syndrome
Rett syndrome
Prader-Willi syndrome
Allergies
Lipid and lipoprotein metabolism disorders
Neurofibromatosis
Williams syndrome
Coffin-Siris syndrome
Optiz-G syndrome
Cornelia de Lange syndrome
Interstitial deletion (q21.3q31)
Globus sensation
Epidermolysis bullosa dystrophica

Reference: PEDIATRIC CLINICS OF NORTH AMERICA, Feb. 2002, page 98

Belly Pain   Air Leaks From Lungs   Acute Crying   Back Pain   Bed Wetting   Big Lymph Node   Big Spleen   Blood in Urine Chronic Diarrhea   Chest Pain   Cough   Coughing Up Blood   Constipation Droopy Eye   Enlarged Glands   Eye Swelling   Excessive Thrist   Facial Paralysis   Fainting Spell   Feeding Problem GI Bleeding   Headache   Head Tilt   Hives   High ESR   Hoarseness   Joint Pain   Limp   Leg Pain   Muscle Weakness   Noisy Breathing   Nose Bleeding   Nose Obstruction   Pyuria   Recurrent Infection   Red Green Urine   Ringing in the Ears Scrotal Swelling     Seizures   Stiff Neck   Swelling of the Parotic Gland   Toe Walking   Toeing In   Toeing Out   Unequal Pupils   Vomiting   Wheezing


Leo Leonidas, MD, FAAP
Assistant Clinical Professor in Pediatrics
Tufts University School of Medicine, Boston

Attending Pediatrician
Eastern Maine Medical Center, Bangor

Bangor, ME: First City with EBPP (Evidence Based Pediatrics for Parents) Website
 

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