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Enlarged Glands

Leo Leonidas MD, FAAP

Why Have a List of Differential Diagnosis?

It is important for clinicians to frequently refer to a list of differential diagnosis so they could ask good questions from the patient or parent. A good clinical history depends on a complete list of differential diagnosis of the chief complaint or main problem.

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CAUSES OF ENLARGED LYMPH NODES

Systemic Infection
Bacterial (sepsis, salmonella, syphilis, etc)
Viral (mono, rubella, CMV, enteroV)
Others (TB, mycoplasma, malaria, Toxoplasmosis, rickettsia)

Malignancy
Acute stem cell Leukemias
Neuroblastoma
Histiocytosis X

Immunologic Dis
Chronic Granulomatous Dis
Serum Sickness
Autoimmune Hemolytic - Anemia
AIDS
Immunoblastic Lymphadenopathy

Drug Reaction
Diphenhydantoin
Others (ASA, barbitureates, penicillin,
Tetracycline, iodides, sufa)

Storage Disease
Gaucher Disease
Niemann-Pick

Collagen Vascular
JRA
SLE

Endocrine
Hyperthyroidism
Adrenal Insufficiency

Misc
Gianotti Crosti
Angiofollicular Lymph Node Hyperplasia
Sarcoidosis
Chediak Higashi Syndrome

Reference:
Signs & Symptoms in Pediatrics
2nd Edition, page 49
Tunnessen, Jr

Belly Pain   Air Leaks From Lungs   Acute Crying   Back Pain   Bed Wetting   Big Lymph Node   Big Spleen   Blood in Urine Chronic Diarrhea   Chest Pain   Cough   Coughing Up Blood   Constipation Droopy Eye   Enlarged Glands   Eye Swelling   Excessive Thrist   Facial Paralysis   Fainting Spell   Feeding Problem GI Bleeding   Headache   Head Tilt   Hives   High ESR   Hoarseness   Joint Pain   Limp   Leg Pain   Muscle Weakness   Noisy Breathing   Nose Bleeding   Nose Obstruction   Pyuria   Recurrent Infection   Red Green Urine   Ringing in the Ears Scrotal Swelling     Seizures Stiff Neck   Swelling of the Parotic Gland   Toe Walking   Toeing In   Toeing Out   Unequal Pupils   Vomiting   Wheezing
 

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