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Coughing Up Blood
Leo Leonidas MD, FAAP
Why Have a List of Differential Diagnosis?
It is important for clinicians to frequently refer
to a list of differential diagnosis so they could
ask good questions from the patient or parent. A
good clinical history depends on a complete list of
differential diagnosis of the chief complaint or
main problem.
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CAUSES OF COUGHING UP BLOOD
Coughing up blood (Hemoptysis) is a frightening episode for a parent or child. Most of the time the blood is coming from the throat. Hemoptysis is not a common reason for visiting an emergency room or a physician. True coughing up of blood is a result of the following conditions: lung infections, bronchiectasis, cystic fibrosis, or aspirated foreign body.
INFECTIONS
Pneumonia Pulmonary Tuberculosis Cystic Fibrosis Bronchiectasis Lund Abscess Pertussis (Whooping cough) Inlfuenza Aspergillosis Coccidiodomycosis Blastomycosis Hemorrhagic Fevers Paragonimiasis
INJURY
Lung Contussion Foreign Body Smoking Clove of Cigarettes
CARDIOVASCULAR CAUSES
Pulmonary Embolus Multiple Pulmonary Telangiectasis Ruptured Arteriovenous Fistula Mitral Stenosis Endomyocardial Fibrosis Necrotic Pulmonary Arterial Lesions
TUMORS
Bronchogenic Cyst Enterogenic Cysts Mediastinal Teratoma Bronchial Submucosal Gland Tumor Plasma Cell Granuloma of Lung Bronchogenic Carcinoma (Rare is childhood)
OTHERS Hemorrhagic Disorders Sickle-Cell Anemia Primary Pulmonary Hemosiderosis Pulmonary Hemorrhage Wegener Granulomatosis Systemic Lupus Erythematosus (SLE) Sarcoidosis Swyer-James Syndrome
BLEEDING WITHOUT LUNG INVOLVEMENT
Nose bleeding (Epistaxis) Injury to the mouth or throat Acute tonsillitis Gingivitis
REFERENCE: Signs & Symptoms In Pediatrics 2nd Edition, page 294 Tunnessen, Jr
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CAUSE OF MASSIVE COUGHING OF BLOOD WITHOUT PREVIOUSLY KNOWN LUNG DISEASE
Airway Hemangioma Pulmonary Sequestration Foregut Duplication Congenital Arteriovenous Malformation Hereditary Hemorrhagic Gelangiectasia Bronchial Adenoma Bleeding Disorder Catamenial Hemoptysis Bronchial Artery Aneurysm Unilateral Pulmonary Artery Agenesis Ehler-Danlos Syndrome Long-Term Trahceostomy Idiopathic Hemoptysis
Reference: THE JOURNAL OF RESPIRATORY DISEASES FOR PEDIATRICIANS, April 2002, page70
Belly Pain Air Leaks From Lungs Acute Crying Back Pain Bed Wetting Big Lymph Node Big Spleen Blood in Urine Chronic Diarrhea Chest Pain Cough Coughing Up Blood Constipation Droopy Eye Enlarged Glands Eye Swelling Excessive Thrist Facial Paralysis Fainting Spell Feeding Problem GI Bleeding Headache Head Tilt Hives High ESR Hoarseness Joint Pain Limp Leg Pain Muscle Weakness Noisy Breathing Nose Bleeding Nose Obstruction Pyuria Recurrent Infection Red Green Urine Ringing in the Ears Scrotal Swelling Seizures Stiff Neck Swelling of the Parotic Gland Toe Walking Toeing In Toeing Out Unequal Pupils Vomiting Wheezing
Leo Leonidas, MD, FAAP Assistant Clinical Professor in Pediatrics Tufts University School of Medicine, Boston Attending Pediatrician Eastern Maine Medical Center, Bangor
BANGOR, MAINE: "First City with EBPP (Evidence Based Pediatrics for Parents) Website"
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