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Big Spleen
Leo Leonidas MD, FAAP

WARNING, WARNING, WARNING; This section is for my Tufts University medical students. If you are a "worrier" type or a very anxious parent, please talk to your clinician about your child's problem or symptoms, rather than reading this differential diagnosis.

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CAUSES OF BIG SPLEEN

IINFECTIONS
Bacterial
Tuberculosis
Brucellosis
Salmonelosis
Viral
Cytomegalovirus
E B virus (mono)
Hepatitis A B C
HIV
Parasitic
Malaria
Toxoplamosis
Syphilis
Leishmaniasis
Pneumocystis carinii
Fungal
Systemic Candidiasis
Aspergillosis

NEOPLASTIC (CANCER0
Leukemia
Lymphoma
Langerhams cell histiocytosis
Hepatoblastoma
Hemangioma
Metastatic neuroblastoma
Wilms tumor

COLLAGEN VASCULAR DISEASE
Systemic Lupus Erythematosus
Juvenile Rheumatoid Arthritis

HEMOLYTIC ANEMIAS
Hereditary spherocytosis
Erythroblastosis fetalis
Thalassemia major
Hemoglobinopathies
Autoimmune Hemolytic
Anemia

STORAGE DISEASE
Glycogen Storage Disease
Gaucher Diseases
Gangliosidosis
Amyloidosis
Alpha 1 antitrypsin dis
Mucopolysaccharidosis
Niemann Pick Disease

OTHERS
Cirrhosis w/ portal hypertension
CHF (mainly hepatomegaly)
Malnutrition

Belly Pain   Air Leaks From Lungs   Acute Crying   Back Pain   Bed Wetting   Big Lymph Node   Big Spleen   Blood in Urine Chronic Diarrhea   Chest Pain   Cough   Coughing Up Blood   Constipation Droopy Eye   Enlarged Glands   Eye Swelling   Excessive Thrist   Facial Paralysis   Fainting Spell   Feeding Problem GI Bleeding   Headache   Head Tilt   Hives   High ESR   Hoarseness   Joint Pain   Limp   Leg Pain   Muscle Weakness   Noisy Breathing   Nose Bleeding   Nose Obstruction   Pyuria   Recurrent Infection   Red Green Urine   Ringing in the Ears Scrotal Swelling     Seizures   Stiff Neck   Swelling of the Parotic Gland   Toe Walking   Toeing In   Toeing Out   Unequal Pupils   Vomiting   Wheezing


End

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