RLS and Strep or MP

RLS and Strep or Mycoplasma


	I have two patients, a 20 month old girl and 12 years old boy, with Restless Leg Syndrome. The boy is better on DHA 400 mg. I was not able to determine the cause of their RLS. Pediatr Neurol. 2004 Aug;31(2):119-21. Restless legs syndrome: association with streptococcal or mycoplasma infection. Matsuo M, et al Department of Pediatrics, Faculty of Medicine, Saga University, Saga, Japan. Group A beta-hemolytic streptococcal infections have been reported to cause neuropsychiatric symptoms, such as chorea, tics, and obsessive-compulsive disorder, presumably through autoimmune damage to basal ganglia. Mycoplasma pneumoniae infections have also been reported to cause damage to the basal ganglia. Restless legs syndrome is a movement disorder with focal restlessness, an irresistible desire to move, and exacerbation by long periods of sitting or lying. We present three children with transient restless legs syndrome-like symptoms possibly associated with group A beta-hemolytic streptococcal infection or Mycoplasma pneumoniae infection. One of three patients had persistently elevated enzyme-linked immunosorbent optical density values against human caudate and putamen. PMID: 15301831 [PubMed - indexed for MEDLINE]

Restless legs syndrome: association with streptococcal or mycoplasma infection.